New research highlights combined impact of genes and lifestyle on dilated cardiomyopathy

Mihaela Măncilă

Victor Chang Cardiac Research Institute Aug 12 2025 An international team, led by scientists from the Victor Chang Cardiac Research Institute has studied around 3000 people affected by the heart disease dilated cardiomyopathy (DCM) – a driver of heart failure and sudden cardiac arrest. They discovered those who had a mutation in a particular gene called TTN were 21 times more likely to develop the disease than family members who did not carry a mutation. For the first time, the team found that

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