POT1 gene mutation linked to pulmonary fibrosis through telomere dysfunction

Mihaela Măncilă

Centro Nacional de Investigaciones Oncológicas (CNIO) Sep 18 2025 Idiopathic pulmonary fibrosis is a potentially fatal disease currently without treatment, in which lung tissue develops scarring and becomes stiff, making breathing increasingly difficult over time. The process is not yet well understood at the molecular scale and is being actively researched. We know that pulmonary fibrosis is strongly linked to dysfunctional telomeres, the structures that protect chromosomes. This finding was

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