Compuscript Ltd Apr 20 2026 A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival, revealing a potential strategy for selectively targeting tumours associated with one of the most common mutations in colorectal cancer. The research identifies ALDH2, an enzyme involved in cellular detoxification, as a critical factor in maintaining viability in cells lacking functional APC. Through a combination of computational screening and