Regenstrief Institute Oct 13 2025 A multi-center randomized controlled trial with critically ill adults aged 50 years and older admitted to intensive care units (ICUs) found that twice-daily slow-tempo music (60 to 80 beats per minute) did not shorten the duration of delirium or coma, or reduce delirium severity, pain or anxiety compared with a silence-track control. While the trial did not mitigate delirium, it showed a trend to fewer days with delirium/coma among patients who received at