Deformability helps cancer cells squeeze through tight tissue gaps, study shows

Raluca Maniță

American Institute of Physics Nov 18 2025 Aggressive cancer cells are masters of movement. When they spread through the body, they cause metastasis, which significantly reduces a person's chance of survival. For this spreading to take place, they can switch between different cell states - behaviors of cells - that move with different strategies. A previous study revealed two specific metastatic cancer lines - MV3 ( melanoma ) and HT1080 (fibrosarcoma) - are capable of making a similar switch

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