DiffInvex identifies key genes driving chemotherapy resistance
Raluca Maniță
Institute for Research in Biomedicine (IRB Barcelona) May 13 2025 Just as species adapt over generations, our body's cells accumulate DNA changes throughout life. Most are harmless, yet a few "driver" mutations give a cell a competitive edge and can spark cancer. Chemotherapy then adds a new evolutionary pressure, encouraging further genetic changes that let tumors bounce back. Researchers at IRB Barcelona have developed DiffInvex, a computational framework that tracks how evolutionary
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