Boosting PI31 to restore synaptic function and prevent neurodegeneration
Educatie
Rockefeller University Sep 16 2025 One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the delicate machinery that keeps neurons in touch-by clearing away protein waste at the synapses-starts to fail. When the cleanup falters, t he connections between brain cells is impaired and the flow of signals responsible for reasoning, language, memory, and even basic bodily functions is progressively disrupted. Now, a new study identifies a
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