Boosting PI31 to restore synaptic function and prevent neurodegeneration

Educatie

Rockefeller University Sep 16 2025 One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the delicate machinery that keeps neurons in touch-by clearing away protein waste at the synapses-starts to fail. When the cleanup falters, t he connections between brain cells is impaired and the flow of signals responsible for reasoning, language, memory, and even basic bodily functions is progressively disrupted.  Now, a new study identifies a