A baby who stopped smiling has been diagnosed with a devastating, rare disease that doctors initially thought was reflux. The inherited condition attacks the nervous system and affects approximately one in 100,000 people across the globe, with baby Otto currently being the only known case in the UK. Otto Sparkes, now four months old, was diagnosed with Krabbe leukodystrophy in May 2026. Doctors originally put his symptoms down to standard reflux and colic until he underwent a lumbar puncture