Harmful DNA changes in the sperm found to rise sharply with age
Raluca Maniță
Wellcome Trust Sanger Institute Oct 8 2025 Harmful genetic changes in sperm become substantially more common as men age because some are actively favored during sperm production, new research has revealed. In a landmark study published today (8 October) in Nature , researchers from the Wellcome Sanger Institute, in collaboration with the TwinsUK study at King’s College London, have comprehensively mapped how harmful DNA changes in sperm cells can increase across the genome as men age. The
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