Medical University of South Carolina Jul 14 2025 Researchers at MUSC Hollings Cancer Center have identified a signaling loop involved in the growth and persistence of leukemia cells – and developed a novel immunotherapy that can disrupt that loop to boost immune function and improve survival. The findings, published in Nature Communications, offer new hope for treating and preventing cancer. Hollings researcher Sophie Paczesny, M.D., Ph.D., co-leader of the Cancer Biology and Immunology