By Priyanjana Pramanik, MSc. Reviewed by Susha Cheriyedath, M.Sc. Nov 19 2025 New evidence shows that colic is usually a benign gut–brain interaction disorder, and only infants with additional allergic symptoms should undergo a structured cow’s-milk elimination and reintroduction trial. Study: I nfantile Colic: When to Suspect Cow’s Milk Allergy. Image Credit: Jirapong Manustrong / Shutterstock In a recent review published in the journal  Nutrients , researchers evaluated existing evidence on