Cedars-Sinai Medical Center Apr 8 2026 A large, long-term study led by Cedars-Sinai Health Sciences University investigators suggests that some medications commonly prescribed to treat irritable bowel syndrome (IBS)-including antidepressants-may be associated with a small but measurable increase in the risk of death. The findings , published in Communications Medicine , are based on nearly two decades of electronic health records from more than 650,000 U.S. adults with IBS, making it the