Study unveils powerful strategy to rejuvenate effectiveness of CAR T cell therapy against glioblastoma

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Fondazione Telethon Jul 3 2025 A team of researchers from the San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET, Milan), led by Nadia Coltella and Luigi Naldini, has unveiled a powerful strategy to rejuvenate the effectiveness of chimeric antigen receptor (CAR) T cell therapy against glioblastoma, one of the most lethal and treatment-resistant brain tumors. The findings, published in Science Translational Medicine , highlight how gene therapy targeting immune stimulating cytokines to

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