Pathogenic mechanisms of Fusobacterium nucleatum in colorectal cancer and emerging therapies
Tratamente medicale
Research journal Jul 12 2025 In recent years, the regulatory role of the gut microbiota in the initiation and progression of colorectal cancer (CRC) has attracted growing attention. Among the key microbial contributors, Fusobacterium nucleatum (Fn) has been identified as a critical pathogenic factor in CRC. As an oral anaerobic commensal, Fn is rarely found in the lower gastrointestinal tract of healthy individuals. However, under pathological conditions, it can ectopically colonize the
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