Triglyceride-lowering drug olezarsen fails to reduce arterial plaque

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American College of Cardiology Mar 30 2026 Despite experiencing significant reductions in triglycerides, patients with triglycerides over 150 mg/dL and a high risk of atherosclerosis did not experience any significant change in the amount of non-calcified plaque in their coronary arteries after taking the triglyceride-lowering drug olezarsen, in a one-year sub-study presented at the American College of Cardiology's Annual Scientific Session (ACC.26). Triglycerides are particles of fat in the

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