By Pooja Toshniwal Paharia Reviewed by Susha Cheriyedath, M.Sc. Feb 26 2026 Preclinical studies increasingly place circular RNAs at the intersection of thermogenic programming and organelle stress control, raising the possibility that these stable RNA loops could eventually inform how metabolic disease is diagnosed and treated.  Cellular changes and associated mechanisms of fat transformation: fat browning is regulated by the central nervous system, peripheral nervous system, transcription