Wiley Apr 22 2026 A study published in Rheumatology & Autoimmunity challenges the assumption that achieving clinical remission in rheumatoid arthritis is sufficient, showing that patient-reported outcomes vary significantly by drug class even when disease activity is comparable. Investigators found that patients taking TNF inhibitors reported better energy levels, mood, and emotional wellbeing than those taking older conventional drugs, while IL-6 and JAK inhibitors showed particular advantages