A genetic variant modulates interferon signaling and disease risk
Coronavirus
University of Colorado at Boulder Dec 13 2024 Why does the COVID-19 virus make some people sicker than others? For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There, when our cells sense an infection, they release a protein known as interferon, which warns other cells to fight the virus. Studies show that when this signaling goes awry and leads the body to under or overreact, people are more likely to develop
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