Cross-reactive T cells link SARS-CoV-2 to autoimmune triggers in MIS-C
Coronavirus
By Tarun Sai Lomte Reviewed by Susha Cheriyedath, M.Sc. Aug 8 2024 A recent study published in the journal Nature evaluated differential autoreactivity to human and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteomes in SARS-CoV-2-infected children with and without multisystem inflammatory syndrome (MIS-C). SARS-CoV-2 typically causes mild illness in children but can lead to MIS-C, a rare, life-threatening condition. This condition presents with a complex and heterogeneous
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