Leritrelvir shows high efficacy against SARS-CoV-2 protease mutations
Coronavirus
Higher Education Press Nov 6 2024 Over the last few years, the SARS-CoV-2 virus, responsible for COVID-19, has undergone significant changes, evolving from the original wild-type strains to the highly transmissible Omicron variant. Omicron has been particularly concerning due to its ability to evade immune protection from vaccines and monoclonal antibodies developed against earlier strains. A critical player in the virus's life cycle is the main protease (M pro ), also known as NSP5 or 3CL
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