New quinoline-based antiviral shows strong promise against SARS-CoV-2
Coronavirus
By Dr. Liji Thomas, MD Reviewed by Benedette Cuffari, M.Sc. Apr 10 2025 A study revealed that Jun13296, a novel PLpro inhibitor, demonstrates potent antiviral and anti-inflammatory effects in vivo, offering hope for future COVID-19 therapies beyond Paxlovid. Study: Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates . Image Credit: Shutterstock AI Generator / Shutterstock.com A study recently published in Nature Communications discusses the
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