Austocystin D's anticancer efficacy linked to CYP2J2 enzyme activity
DNA
Tokyo University of Science Aug 27 2024 Austocystin D, a natural compound produced by fungi, has been recognized for its cytotoxic effects and anticancer activity in various cell types. It exhibits potent activity even in cells that express proteins associated with multidrug resistance, attracting significant global research interest. Austocystin D promotes cell death by damaging their DNA, a process which might be dependent on cytochrome P450 (CYP) oxygenase enzymes. Notably, austocystin D has
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