Cells detect and silence invading transposons through abnormal RNA signals
DNA
St. Jude Children's Research Hospital May 26 2026 Transposons, DNA sequences that can self-replicate and move (jump) throughout the genome, are widespread and can affect cell survival if left unchecked. Cells control these "jumping genes" by silencing them, but little was known about how cells recognize and defend themselves from invading transposons. St. Jude Children's Research Hospital scientists have answered that question, showing that cells sense abnormal RNA patterns produced by invading
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