Epstein-Barr virus triggers inflammatory cell death in ulcerative colitis
DNA
Chinese Academy of Sciences Mar 24 2025 Ulcerative colitis (UC) is a chronic, relapsing disease that causes painful inflammation and ulcers in the colon. While its exact causes remain elusive, mounting evidence suggests that viral infections, particularly Epstein-Barr virus (EBV), may worsen disease severity. Elevated EBV DNA and RNA levels have been detected in the colonic tissues of UC patients, correlating with more aggressive symptoms, higher risks of surgery, and poorer treatment responses.
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