Fever enhances immune cell activity and induces mitochondrial stress
DNA
Vanderbilt University Medical Center Sep 20 2024 Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also -; in a particular subset of T cells -; cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered. The findings, published Sept. 20 in the journal Science Immunology , offer a mechanistic understanding for how cells respond to heat and could explain how chronic inflammation contributes to the
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