FUSE: Revolutionizing the analysis of gene mutations
DNA
Brigham and Women's Hospital Oct 25 2024 How would you summarize your study for a lay audience? Our study introduces a new tool called FUSE (Functional Substitution Estimation) that helps scientists better understand how changes in genes affect proteins. Genetic variants can alter how a protein works, potentially leading to diseases. New CRISPR-based experiments can help us understand the impact of genetic variants by installing these changes into the DNA of cells. FUSE combines data from many
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