New imaging method maps DNA replication forks with single-cell resolution
DNA
University of Texas M. D. Anderson Cancer Center Apr 28 2026 Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that quantitatively detects and maps reversed DNA replication forks with single-cell resolution. The results also demonstrated a unique epigenetic code for DNA replication stress that can be further examined to understand mechanisms of genomic stability, aging and treatment response. The study, published in Nature
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