New mechanism to enhance precision in cancer drug development
DNA
University of Texas Medical Branch May 15 2026 Researchers at The University of Texas Medical Branch (UTMB) have identified how a key enzyme called ATR protects DNA from breaking when cells copy damaged genetic material, a discovery that could affect how certain cancer drugs are developed. Funded by the National Institutes of Health and published in Genes & Development , the study shows how ATR helps stabilize the cell's DNA-copying machinery during replication stalls, preventing chromosomes
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