New study links inherited mitochondrial DNA mutation to disrupted immune balance

DNA

Trinity College Dublin Nov 26 2025 Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have discovered that this single inherited mutation causes whole-body issues in an animal model after its immune response is sparked into action. Although the scientists stress the research is at a relatively early stage, it is one of the first pieces of work to show that

Tag-uri: DNA

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