New Technique Maps Hundreds of Proteins Simultaneously within Cell Nuclei
DNA
Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell nuclei all at the same time. The method, called ChIP–DIP (Chromatin ImmunoPrecipitation Done In Parallel), is a versatile tool for understanding the inner workings of the nucleus during different contexts, such as disease or development. The research was conducted in the laboratory of Mitchell Guttman , professor of biology, and is described in a paper that appears in the
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