One letter DNA change switches sex development in mice
DNA
Bar-Ilan University Apr 9 2026 Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development in mice. In the new study, published in Nature Communications , a single-letter insertion in a non-coding regulatory region caused XX mice, which would normally develop as females, to develop instead as males with testis and male genitalia. The finding is especially striking because the mutation was not made in a gene itself, but in a
din zilele anterioare