From biomodal Aug 30 2024 An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene expression. Reversing this modification requires DNA demethylation, a series of enzymatic reactions which starts with the creation of 5-hydroxymethylcytosine (5hmC). But 5hmC is not just a transient step in the DNA demethylation pathway but represents an important epigenetic

Tag-uri: DNA