Researchers uncover nuclear organization mechanism linked to Friedreich's ataxia
DNA
University of Pennsylvania School of Medicine May 12 2026 Researchers have uncovered a fundamental rule that governs how genes are physically arranged inside the cell nucleus, and how disruptions to that organization can contribute to human disease. Researchers at the Perelman School of Medicine at the University of Pennsylvania found that a balance between gene activity and the cellular machinery that folds and organizes DNA determines whether genes are pushed to the edge of the nucleus, where
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