Rethinking the mitochondrial theory of aging
DNA
University of Tsukuba May 27 2025 The human genome is broadly classified into the genome residing in the cell nucleus (nuclear DNA) and the genome residing in the mitochondria (mitochondrial DNA: mtDNA). Mitochondria are cell organelles that produce energy essential for life activities through oxidative phosphorylation (mitochondrial respiration), and mtDNA encodes a set of genes required for mitochondrial respiration. Previous research has led to the widely accepted hypothesis that the
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