Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

DNA

Nazarbayev University Oct 17 2025 A new review in Clinical Epigenetics synthesises growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter sperm epigenetic marks (DNA methylation, histone retention, and small non-coding RNAs). These changes can influence sperm quality and fertilising ability, early embryo development, assisted reproduction outcomes, and long-term health risks in offspring. Key findings

Tag-uri: DNA

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