Scientists discover on/off gene switches that could revolutionize personalized medicine
DNA
By Priyanjana Pramanik, MSc. Reviewed by Susha Cheriyedath, M.Sc. Jun 22 2025 Scientists identified 473 human genes that act as genetic “on/off switches,” shaping disease risk through tissue-specific or universal patterns regulated by DNA changes and hormones. Study: Switch-like gene expression modulates disease risk . Image Credit: gopixa / Shutterstock In a recent article published in Nature Communications , researchers analyzed methylomes, transcriptomes, and genomes from 943 individuals
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