UCLA study reveals key role of mismatch repair genes in Huntington’s disease
DNA
University of California - Los Angeles Health Sciences Feb 11 2025 A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies. Huntington's disease is one of the most common inherited neurodegenerative disorders that
din zilele anterioare