Durham University Nov 26 2024 Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent in humans, plays a crucial role in supercoiling DNA, a necessary process for bacterial survival. Using high-resolution cryo-electron microscopy the researchers reveal unprecedented detail of gyrase's action on DNA,

Tag-uri: Medicamente DNA