Iran’s supreme leader has issued a stark ultimatum to U.S. President Donald Trump, escalating the long-running standoff between Tehran and Washington. Ayatollah Ali Khamenei declared that Iran would not engage with the United States unless it abandoned its support for Israel, pulled its forces out of the Middle East and ended all interference in regional affairs. Newsweek has contacted the U.S. State Department and Iran’s Foreign Ministry for comment. Khamenei’s remarks highlight a persistent

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