New X-ray technique reveals metal ion role in antibiotic efficacy
Medicamente
City St George's, University of London Oct 4 2024 Researchers from City St George's, University of London have used a new ultra-high precision x-ray scattering technique to unveil the location and identity of metal ions in bacteria that are crucial for antibiotics to work optimally. Many types of bacteria produce an enzyme molecule called topoisomerase IV, which disentangles and separates newly-replicated DNA in complex structures within bacteria to enable the cells to divide and multiply.
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