Science and Technology Review Publishing House Mar 6 2026 Professor Chao Zhang's team at Zhujiang Hospital, Southern Medical University, has developed a novel DNA nanomachine-based drug delivery and release strategy aimed at overcoming chemoresistance in small cell lung cancer (SCLC). The team identified the PRMT1/SOX2 signaling axis as a key driver of chemotherapy resistance in SCLC and, based on this mechanism, designed a DNA nanomachine capable of temporally programmed drug release. By

Tag-uri: DNA