University of Minnesota Medical School Oct 31 2025 New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, turning the cell's busiest receptors into precision tools - opening the door to a new generation of safer, smarter medicines. The findings were published today in  Nature . About one-third of all drugs approved by the Food and Drug Administration