By Priyanjana Pramanik, MSc. Reviewed by Susha Cheriyedath, M.Sc. Nov 20 2025 New findings from the Framingham Heart Study show that staying active in midlife and late life has a powerful impact on long-term brain health and may significantly reduce the risk of dementia. Study: Physical Activity Over the Adult Life Course and Risk of Dementia in the Framingham Heart Study. Image Credit: Master1305 / Shutterstock In a recent study published in JAMA Network Open , researchers examined whether