Zhong et al. report the critical role of oncogenic KRAS/ERK/JUNB signaling in suppressing GATA6, the master regulator of differentiation in pancreatic cancers. Key proteins in pancreatic cancer xenografts were detected by immunohistochemical staining, with the resulting photomicrographs enhanced in color and texture with the DeeVid AI tool. Credit: Zheng Zhong and Xinang Cao, Duke-NUS Medical School Researchers at Duke-NUS Medical School have discovered a molecular "switch" that determines