Breakthrough study maps impact of thousands of variants in heart disease gene

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Vanderbilt University Medical Center Oct 31 2025 An international research consortium co-led by scientists from Vanderbilt University Medical Center, the University of Toronto and University of Pittsburgh has mapped the functional impact of more than 17,000 variants in a major gene associated with the development of premature atherosclerotic heart disease. The study, reported Oct. 30 in the journal Science , will go a long way to improving the early diagnosis and treatment of familial

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