The University of Osaka Jul 10 2025 Our genes underlie all aspects of life, from our looks to how our cells behave. This includes diseases, as genetic changes can underlie the development and progression of certain health problems. This is true for arteriovenous malformations (AVMs), vascular anomalies that are known to be life-threatening. However, the biological mechanisms driving their growth have remained unclear, until now. AVMs are tangled clusters of abnormal blood vessels that can cause