American Heart Association Oct 31 2025 Pulmonary embolism (PE), a type of blood clot in the lungs, sends more than half a million people to U.S. hospitals each year - and kills about one in five high-risk patients, according to the American Heart Association 2025 statistical update. PE is the third leading cause of cardiovascular death in the U.S. While progress has been made in PE care, pulmonary embolism remains underdiagnosed, undertreated and inconsistently managed. To address these gaps in