University of Seville Oct 30 2025 A multidisciplinary research team has discovered that liver alterations associated with metabolic dysfunction-associated fatty liver disease (MASLD) can directly cause cognitive and neurological impairments, and that these effects can be reversed by a therapy exclusively targeting the liver. The findings, published in Science Advances, establish the existence of a "liver-brain axis" that is not only clinically relevant but also therapeutically actionable. The