Vanderbilt University Medical Center Jun 15 2026 An international team of researchers has identified a genetic cause for a rare inflammatory skin condition.  The investigators report in the journal Nature Immunology that a mutation in the gene OTULIN causes pediatric-onset pyoderma gangrenosum characterized by recurrent ulcerating skin sores. They classify the condition as a new inborn error of immunity (IEI) - one of a group of more than 500 genetic disorders that impair the development or