Large clinical trial shows both common septic shock fluids are equal
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Ann & Robert H. Lurie Children's Hospital of Chicago Jun 5 2026 A randomized clinical trial conducted across five countries in 47 pediatric emergency departments, including Ann & Robert H. Lurie Children's Hospital in Chicago, established that both commonly used IV fluids for treating septic shock – balanced crystalloid fluid and 0.9% saline – are equally safe and effective. Results were published in the New England Journal of Medicine. Septic shock is a life-threatening medical emergency in
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